Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Category: News

New publication from the ME/CFS Collaborative Research Center at Stanford University!

The campus at Stanford University

Today, we are excited to share a new publication by Fereshteh Jahaniani, Ph.D., Ron Davis, Ph.D., & colleagues: “Longitudinal cytokine and multi-modal health data of an extremely severe ME/CFS patient with HSD reveals insights into immunopathology, and disease severity.” This study is supported by OMF and the EDS Society. Read the full publication here! From […]

Sean’s Voice: Living with ME/CFS and the Quest for Understanding!

A before-and-after snapshot of Sean's life. On the left, Sean beams proudly with a writing competition medal. On the right, he lies in a hospital bed, wearing a sleep mask. Sean's quote: "ME/CFS robbed me of my dreams, shattered my independence, leaving me bed-bound and reliant on others."

In the heart of our Open Medicine Foundation Canada family, there are personal stories that bring to light the stark reality of living with ME/CFS and Long COVID. Today, we invite you to witness the profound narrative of Sean Henneberry, a brave soul who has been navigating the turbulent waters of ME/CFS and Postural Orthostatic […]

Final Reminder: Join the Hope Builder Challenge Today!

Collage featuring images of Elise smiling at the camera, lying down in the back seat of a car, and resting with her dog.

Time is running out! Our Hope Builder challenge ends soon, and we need your help to meet our goal of welcoming 30 new monthly donors by the end of March.  Thanks to our community’s passion and generosity, we have already welcomed 17 incredible Hope Builders this month. Now, we’re looking for just 13 more remarkable supporters like you to help us cross the […]

Spring Into Action: Join the Hope Builders Community!

A collage of three pictures of Manon and her partner, Hugo. The first picture is in the gallery, the second in front of the Sydney Opera House, and the third in a park.

Step into spring as a Hope Builder! With the arrival of a season that symbolizes renewal and progress, we at Open Medicine Foundation Canada are inspired by the strength of those living with ME/CFS and Long COVID. This season of new beginnings is the perfect opportunity to step up and make a difference.   Become […]

Standing Together on Long COVID Awareness Day: Let’s Make a Difference Together!

A ribbon in three colors: gray, teal, and black. The text beside the ribbon reads International Long COVID Awareness Day.

Today, we unite in solidarity to observe Long COVID Awareness Day. This day holds profound significance for countless individuals worldwide. We stand together in spirit and purpose, recognizing the extensive impact of SARS-CoV-2. This day serves as a beacon in our collective efforts to raise awareness and bolster support for those living with persistent symptoms following […]

Join the Hope Builders Challenge: Your Monthly Gift Can Ignite Change!

A smiling woman with shoulder-length reddish-brown hair, accompanied by the Hope Builders logo.

Imagine our collective strength when we unite for a cure. At Open Medicine Foundation Canada (OMFCA), we are driven to find effective treatments for ME/CFS and Long COVID. Our global collaboration model harnesses the brightest minds to bring relief to you and your loved ones.   Yet, this monumental task cannot be accomplished alone. This is […]

Let’s Reach 8,000 Now: Sign Up Today!

A group of seven diverse individuals posing in a friendly and cohesive manner, suggesting a collaborative environment. Above the group is a StudyME logo.

Join the Momentum! Finding people with ME/CFS and Long COVID who can participate in studies is one of the biggest barriers to research. You could be the solution! We’re delighted to share that the OMF StudyME Registry has reached a pivotal achievement in our mission to empower medical research. Over 7,700 participants have signed up since we launched. Will you […]

Watch Now: NIH ME/CFS Research Roadmap Webinar Series Recordings!

Overview of webinar topics and images of David Systrom presenting and Linda Tannenbaum networking at the Open Medicine Foundation table.

The ME/CFS Research Roadmap webinars, hosted by the National Institute of Health (NIH), have successfully concluded. These virtual events brought together ME/CFS experts to present current research, identify knowledge gaps, and explore future research opportunities for ME/CFS.    Open Medicine Foundation proudly participated in these webinars, with our team members not only contributing as presenters […]

February 6: New Publication from Jonas Bergquist, MD, PhD, & Colleagues!

Dr. Jonas Bergquist is pictured in his laboratory, wearing a lab coat. Below the image, the title of the publication is displayed.

We are excited to share a new publication from the research funded by Open Medicine Foundation (OMF). Jonas Bergquist, MD, PhD, OMF Chief Medical Officer and Director of the OMF-supported ME/CFS Collaborative Research Center at Uppsala University, and colleagues, have published a study: ‘Analysis of tryptophan metabolites and related compounds in human and murine tissue: development […]

Looking Back and Looking Forward: OMFCA’s 2023 Year in Review!

2023 Year in Review: hands of diverse skin tones connecting pieces of a wooden jigsaw puzzle.

As 2024 begins, we at Open Medicine Foundation Canada are thrilled to review a few highlights and the milestones you made possible in 2023. It was a year filled with incredible achievements, groundbreaking research, and community empowerment.  Thanks to your unwavering support, we’ve reached new heights in our quest to understand and treat ME/CFS, Long COVID and related diseases. We’d […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.